How Too Much Salt and Sugar May Affect Blood Pressure

How Too Much Salt and Sugar May Affect Blood Pressure

Introduction

The modern diet often includes high levels of both salt and added sugars, especially fructose, which is found in many packaged foods and sweetened drinks. While both are known to affect health on their own, a recent trial in healthy adults shows that the combination of high salt and high fructose may work together in ways that could raise blood pressure and affect kidney function—even in young, otherwise healthy people.

What Happens Inside the Body

Normally, our kidneys help maintain a balance by removing extra sodium through urine. This keeps blood pressure in check. But when the diet includes too much fructose along with salt, the kidneys become less efficient at removing sodium. This means more sodium stays in the body, which can cause a rise in blood pressure.

In the trial, participants who had a diet high in both salt and fructose for just one week showed reduced sodium excretion and a small but significant increase in blood pressure. This effect was not seen with high salt alone, suggesting that fructose plays a unique role in disrupting this process.

Inflammation May Also Be Involved

The combination of salt and fructose also raised levels of an inflammatory marker in the blood called interleukin-6 (IL-6). This shows that the body's immune response might also be affected by diet. Inflammation is already linked to many chronic diseases, including high blood pressure, so this finding could be important for long-term health.

Men and Women May Respond Differently

Interestingly, while both men and women were affected by the diet, the changes in blood pressure during sleep (a normal drop that happens at night) were more noticeable in men. This may suggest that some people are more sensitive to the effects of salt and sugar than others, but more research is needed to fully understand these differences.

Why It Matters

Even among healthy young adults, just one week of a high salt and high sugar diet was enough to change how the kidneys and blood vessels work. This suggests that short-term choices may have lasting effects, especially if such eating patterns are common.

The study highlights that it's not just about cutting back on salt or sugar alone—it's about how they interact in the body. Choosing whole foods and reducing both added salt and sugary drinks may help maintain better blood pressure control, support kidney health, and lower inflammation.

Conclusion

Salt and sugar are everywhere in today’s diet, but their combined effect may quietly raise blood pressure and stress the kidneys. By paying attention to both, we can take simple steps toward better long-term health—even before any signs of illness appear.

Reference: https://physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.70284

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