Can Night Shift Work Affect Your Brain Health Later in Life?

Can Night Shift Work Affect Your Brain Health Later in Life?

Night and shift work have long been blamed for causing health issues. Disrupted sleep, fatigue, and poor lifestyle habits often go hand in hand with working odd hours. But what does science say about how these jobs affect our brain health in the long run?

A recent study may surprise you.

What Was the Study About?

Researchers followed a group of British adults who were all born in the same week in 1946. They tracked their health and lifestyle habits over several decades. At age 31, the participants were asked if they worked night or shift jobs. At age 70, they underwent brain scans and blood tests to check for signs of brain aging and Alzheimer’s disease.

The goal was to see if early adult shift work had any long-term effects on brain health and dementia risk.

Surprising Results

The researchers found something unexpected. People who worked night or shift jobs in their 30s had:

  • Smaller brain volumes in older age (which usually indicates more brain aging)
  • Healthier Alzheimer’s markers, including lower levels of harmful proteins linked to the disease
  • Lower risk of non-vascular dementia by age 78

This was despite the fact that shift workers were more likely to smoke, drink more alcohol, and have other health risks.

So, Is Shift Work Good for You?

Not exactly. While the lower dementia rates are surprising, it’s important to look deeper.

Shift workers in the study did have more signs of unhealthy lifestyles, like:

  • More smoking (about 6 more pack-years by age 53)
  • Higher alcohol consumption, especially by age 63
  • Slightly higher heart disease risk

These habits are known to harm the brain over time. In fact, 28% of the reduced brain volume seen in shift workers was linked to these unhealthy behaviors.

Still, they showed less Alzheimer’s disease pathology. That’s unusual, since disturbed sleep has often been linked with more Alzheimer's risk, not less.

What Could Explain This?

There are a few possible explanations:

  • Stronger brains? Maybe only those with more resilient brains can tolerate night shifts, so the healthier brain results are due to selection.
  • Early shift work only? The participants only reported working shifts at age 31. Maybe short-term exposure in youth is different from long-term shift work in later life.
  • Circadian adaptation? Some scientists wonder if the body adapts to night shifts in ways that help the brain later. Think of it like a "workout" for the brain's sleep system.

But right now, these are just theories. More research is needed.

What Does This Mean for You?

If you work night or shift jobs, it’s important to:

  • Watch your lifestyle habits. Smoking, alcohol, and poor sleep can take a toll on your heart and brain.
  • Prioritize good sleep when you're off work
  • Stay physically and mentally active to support brain health

This study doesn’t suggest shift work is protective, but it does challenge some assumptions. It also shows how complex the links between lifestyle, sleep, and brain health really are.

Final Thoughts

Shift work often comes with challenges, especially for long-term health. But the new research adds an interesting twist: not all effects are as bad as we once thought. That said, healthy habits still matter more than ever—especially when you’re working against the clock.

Understanding how work patterns affect our health is important for workers and policymakers alike. For now, the best advice is to focus on sleep, exercise, diet, and stress management, no matter your schedule.

Let’s take care of our brains, one shift at a time.

Reference: https://academic.oup.com/braincomms/advance-article/doi/10.1093/braincomms/fcaf264/8186239

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